Ventricular‐Arterial Function and Coupling in the Adult Fontan Circulation

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Ventricular‐Arterial Function and Coupling in the Adult Fontan Circulation

BACKGROUND In adult Fontan patients, ventricular or arterial dysfunction may impact homeostasis of the Fontan circulation and predispose to heart failure. We sought to characterize ventricular-arterial (VA) properties in adult Fontan patients. METHODS AND RESULTS Adult Fontan patients (n=170), including those with right (SRV, n=57) and left (SLV, n=113) dominant ventricular morphology, were c...

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The Fontan Circulation

The original Fontan procedure was first introduced in the 1970s. The concept behind this surgical technique was revolutionary. It has subsequently transformed the lives of children born with complex congenital heart disease which was once thought to be inoperable and resulted in early death. The procedure itself has had several modifications over the decades, with subsequent improvements in lon...

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Cardiac rest and reserve function in patients with Fontan circulation.

OBJECTIVES In the present study, we systematically tested cardiac rest and reserve function in patients with Fontan physiology to check for inherent limitations of this circulation. BACKGROUND Details of the mechanisms of cardiac performance that could account for adverse outcome after Fontan surgery are not well understood. METHODS The subjects were 17 Fontan patients with good functional ...

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The Fontan circulation.

Correspondence to: Professor Marc Gewillig, Pediatric Cardiology, Gasthuisberg University Hospital, B 3000 Leuven, Belgium; marc.gewillig@ uzleuven.be _________________________ A normal mammal cardiovascular system consists postnatally of a double—pulmonary and systemic—circuit, connected in series, powered by a double pump—the ‘‘right’’ and ‘‘left’’ heart. Many complex cardiac malformations ar...

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Biomarkers and the Fontan Circulation.

A lthough the dramatically improved survival of children with single-ventricle heart disease with Fontan circulation in the recent era is a tremendous accomplishment in pediatric cardiology and cardiac surgery, it has been accompanied by a growing realization that Fontan circulation is largely a state of compensated heart failure at risk for decompensation. Fontan failure occurs in numerous way...

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ژورنال

عنوان ژورنال: Journal of the American Heart Association

سال: 2016

ISSN: 2047-9980

DOI: 10.1161/jaha.116.003887